What are the Precautions When Taking Gabapentin (Neurontin®)?

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Gabapentin (brand name: Neurontin) is a generic prescription drug that is FDA-approved as an add-on treatment with other medications for partial seizures in those with epilepsy. It can also be used to treat nerve pain from postherpetic neuralgia (a complication of shingles).  Gabapentin is frequently prescribed off-label for many other conditions, such as diabetic peripheral neuropathy, fibromyalgia, and alcohol dependence.  Gabapentin is an anticonvulsive medication that originally saw use as a muscle relaxer and anti-spasmodic medication, but later it was discovered it had the potential of the medication as anticonvulsive medication and as an adjunct to more potent anticonvulsants. It is also useful in certain types of neural pain control. This activity outlines the indications, mechanism of action, dosing, significant adverse effects, contraindications, monitoring, and toxicity of gabapentin and increases practitioners'…
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Gabapentin for Fibromyalgia

Gabapentin for Fibromyalgia

Gabapentin Off-Label Usages
What Is Gabapentin? Gabapentin is somewhat commonly prescribed as a fibromyalgia treatment, however, it is not approved by the U.S. Food and Drug Administration (FDA) for this condition. It's often prescribed off-label. However, the drug is chemically related to Lyrica (pregabalin), which is approved for fibromyalgia. In fact, Lyrica is sometimes referred to as the "son of Neurontin." Gabapentin is classified as an anti-seizure drug. It's used to treat epilepsy, neuropathy (pain from damaged nerves), restless legs syndrome, and hot flashes. Fibromyalgia pain is similar to neuropathy, but whether this condition involves nerve damage still isn't clear. [caption id="attachment_310" align="aligncenter" width="512"] gabapentin mechanism of actions[/caption] How Gabapentin Works Gabapentin is believed to work by altering the release of glutamate and other neurotransmitters in your brain.1 Neurotransmitters send messages from one brain cell to…
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Gabapentin Dosage for Adults

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Gabapentin is a prescription drug. It comes as an oral capsule, an immediate-release oral tablet, an extended-release oral tablet, and an oral solution. Gabapentin oral capsule is available as the brand-name drug Neurontin. It’s also available as a generic drug. Generic drugs usually cost less than the brand-name version. In some cases, the brand-name drug and the generic version may be available in different forms and strengths. Why Gabapentin is Used Gabapentin oral capsule is used to treat the following conditions: Seizures: Gabapentin is used to treat partial (focal) seizures. It’s taken together with other seizure medications in adults and in children 3 years of age and older who have epilepsy. Postherpetic neuralgia: This is pain from nerve damage caused by shingles, a painful rash that affects adults. Shingles appears after infection with the…
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Gabapentin Dosage Chart, Gabapentin Dosage for Adults and Gabapentin Dosage for Children

Gabapentin Dosage Chart, Gabapentin Dosage for Adults and Gabapentin Dosage for Children

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Gabapentin is a generic prescription drug that is FDA-approved as an add-on treatment with other medications for partial seizures in those with epilepsy. It can also be used to treat nerve pain from postherpetic neuralgia (a complication of shingles). Gabapentin is frequently prescribed off-label for many other conditions, such as diabetic peripheral neuropathy, fibromyalgia, and alcohol dependence. Gabapentin is typically prescribed as a generic, but the drug is also available under the brand names Neurontin and Gralise. Some patients may be prescribed drugs very similar to gabapentin—such as Horizant (gabapentin enacarbil) or Lyrica (pregabalin)—instead of gabapentin. Gabapentin is taken as a tablet, capsule, or oral liquid. Dosing will depend on the condition being treated, age of the person being treated, and kidney function. The usual dose for epilepsy starts at 300 mg on the…
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What Diseases Gabapentin can treat ?

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Gabapentin was developed to treat epilepsy, but it is now used to treat various forms of chronic pain. It works by reducing the number of signals sent through the nerves. If the signals are reduced then the pain will be reduced. Research has shown that Gabapentin can help in treating various types of nerve pain. Some Research Team performed searches to look for clinical trials where gabapentin was used to treat neuropathic pain or fibromyalgia. They found that 5633 participants had been involved in 37 studies of reasonable quality.  They tested gabapentin against placebo for four weeks or more.  Studies lasting only one or two weeks are unhelpful when pain can last for years. Neuropathic pain is pain coming from damaged nerves. It differs from pain messages carried along healthy nerves from…
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